Leading Cancer Care, Research, and Innovation

Duke Health provides advanced, highly specialized care for patients facing complex, rare, and difficult-to-treat cancers. As home to the Duke Cancer Institute, North Carolina's highest-ranked cancer program and one of the leading U.S. National Cancer Institute Comprehensive Cancer Centers, Duke brings together more than 500 cancer experts, groundbreaking research, innovative therapies, and access to clinical trials that may not be available elsewhere. Patients from around the world turn to Duke for expertise in complex cancers, including brain tumors, pancreatic cancer, sarcomas, and other conditions requiring highly specialized multidisciplinary care.

• Provides advanced cellular and gene therapies for complex and difficult-to-treat cancers, including CAR T-cell therapy for refractory or relapsed blood cancers, T-cell receptor therapy for synovial sarcoma, and tumor-infiltrating lymphocyte therapy for melanoma
• Delivers advanced radiopharmaceutical therapies as a Comprehensive Radiopharmaceutical Therapy Center of Excellence recognized by the Society of Nuclear Medicine and Molecular Imaging, supported by specialized multidisciplinary teams and a robust research program that has helped advance novel treatments for advanced prostate cancer
• Leads innovation in brain tumor care through the Preston Robert Tisch Brain Tumor Center, offering world-renowned expertise in research, clinical trials, and advanced therapies for patients with primary and metastatic brain tumors
• Advances cancer research through a comprehensive clinical trials program that includes disease-specific trial units, an active Phase 1 Center, and a Molecular Tumor Board, while partnering with referring institutions to streamline trial access, referrals, and global research collaborations

Learn more about advanced cancer care at Duke Health. 

Expertise for Complex Conditions

Duke Health offers both children and adults some of the most advanced cell and gene therapies available today. Our team has been involved in many of the clinical trials that led to FDA approval of these therapies and is shaping the future of these treatments. Duke is one of the few programs in the U.S. offering stem cell transplantation as part of treatment for scleroderma; Duke also offers a new, FDA-approved gene therapy that can help alleviate severe pain and other serious complications associated with sickle cell disease.

• Treats more than 140 patients annually with cellular therapies, including CAR-T and TCR therapies
• Uses gene therapy to halt or reverse vision loss from inherited retinal diseases as one of only 15 centers in the U.S.
• Advances treatment for a wide range of potentially fatal diseases through an internationally recognized pediatric stem cell and cellular therapy program and innovative stem cell therapies
• Pioneered a new era of transplant medicine by performing the world’s first unrelated donor cord blood transplant in 1993
• Provides access to innovative clinical trials evaluating cell and gene therapies for a broad range of conditions, including beta thalassemia, sickle cell disease, primary immune deficiencies, and autoimmune diseases

Learn more about cell and gene therapy at Duke Health (PDF). 

Expertise for Your Most Complex Eye Conditions

Duke Health provides specialized, personalized care for patients with complex eye diseases and vision disorders. Ranked among the top U.S. ophthalmology programs, Duke combines highly specialized clinical expertise with leading innovations in surgical techniques, imaging, and vision research to help protect, restore, and preserve sight.

• Nationally recognized ophthalmology program ranked among the nation’s best by U.S. News & World Report
• Innovative diagnostic tools, advanced surgical techniques, and research-driven therapies
• Groundbreaking discoveries, including the breakthrough that led to the first FDA-approved glaucoma therapy in more than 20 years
• Comprehensive, personalized care for patients of all ages and levels of complexity
• Renowned physician leaders advancing the future of eye care through research, education, and clinical innovation

Learn more about advanced eye care at Duke Health (PDF). 

Global expertise for complex cardiovascular disease across the lifespan

Duke Heart & Vascular is among the leading U.S. academic cardiovascular programs delivering advanced adult, pediatric, and congenital heart care. Our multidisciplinary teams combine clinical expertise, research, innovation, and specialized surgical and interventional capabilities to care for patients with complex cardiovascular conditions from around the world.

• Consistently recognized for excellence in cardiovascular care, with U.S. News & World Report high-performing ratings across multiple heart and vascular specialties and the highest STS 3-star ratings for adult cardiac surgery
• Among the largest ventricular assist device (VAD) and heart transplant programs by volumes in the U.S.
• Access to emerging therapies, advanced procedures, and research-informed treatment strategies
• One of the few U.S. hospitals verified as a Level 1 Children’s Surgery Center by the American College of Surgeons

Learn more about adult and pediatric heart care at Duke Health (PDF).

Expertise for Your Most Complex Adult and Pediatric Neurological Conditions

Duke Health is recognized for its expertise in spine and neurosurgery, providing state-of-the-art, interdisciplinary care for conditions such as brain tumors, epilepsy, stroke, Parkinson disease, spinal tumors, spine trauma and deformity, and degenerative disc disease, using advanced technologies and minimally invasive techniques.

• Advanced neurosurgical technologies, including deep brain stimulation, laser interstitial thermal therapy, high-intensity focused ultrasound, stereotactic radiosurgery, and responsive neurostimulation
• One of the few centers in the U.S. with the expertise to diagnose and treat cerebrospinal fluid leaks
• Preston Robert Tisch Brain Tumor Center specialists co-developed a vaccine that extends the lives of
  people with glioblastoma
• One of the few U.S. hospitals verified as a Level I Children's Surgery Center by the American College of
  Surgeons
• Designated Level 4 Epilepsy Center by the National Association of Epilepsy Centers
• Access to new therapies for adult and pediatric patients eligible for clinical trials
• Leader in minimally invasive solutions to spine pathology, including endoscopic and awake spine surgery
• Serves 30,000+ spine patients annually and performs 3,000+ spine surgeries each year
• Duke University Hospital is a Level I Trauma Center, providing the highest level of emergency
  care for spinal injuries

Learn more about advance neurosciences (PDF) and spine care (PDF) at Duke Health.

Global Expertise for Adult and Pediatric Complex Musculoskeletal Conditions

Duke Orthopaedics is a leading academic orthopaedic program that combines clinical excellence, research, innovation, and multidisciplinary expertise to advance musculoskeletal care. Our specialists care for patients with complex orthopaedic conditions from around the world, including challenging primary cases, revision procedures, and conditions requiring highly coordinated subspecialty care.

• Pioneered several surgical breakthroughs, including novel fracture repairs and advanced surgical techniques
• Helped develop commonly used ankle, shoulder, and elbow joint prostheses
• Uses sophisticated outcomes research tools to measure surgical success, refine techniques, and expand treatment options to improve patient outcomes

Learn more about advanced orthopaedic care at Duke Health (PDF).